Erythema multiforme minor

Rhinitis (sneezing, rhinorrhea) Erythema multiforme minor... 

Some regimens are designed for outpatient administration over much longer time periods and have been used, for example, with allopurinol dermal reactions. Such late-onset morbiliform reactions, sometimes overlapping with erythema multiforme minor, are difficult to evaluate because it is often unclear to what extent the patients were at risk for recurrent reaction. 

Erythema multiforme minor is comparatively benign. SJS or EMM involves the ocular tissues and produces the classic signs of a catarrhal pseudomembranous conjunctivitis. Erythema multiforme occurs more frequently in men than in women. 

In 87 patients with multiple myeloma in an open trial given thalidomide alone (n = 50) or thalidomide + dexamethasone (n = 37), there were minor to moderate skin eruptions in 23 patients taking thalidomide alone and in 16 of those taking thalidomide + dexamethasone (80). These included morbilliform, seborrheic, maculopapular, and non-specific dermatitis. Three patients taking thalidomide + dexamethasone had severe skin reactions (exfoliative erythroderma, erythema multiforme, and toxic epidermal necrolysis) that required hospitalization and withdrawal of thalidomide. 

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