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Ervatamia dichotoma

The related alkaloids ervaticine (15) and apparicine (16a) have been isolated from the leaves of Ervatamia coronaria (85H(23)2975) and from the wood of Vallesia antillana (77MI249), respectively. The latter exhibits high antibacterial activity. Subsequently, 16(S)-hydroxy-16,22-dihydroapparicine (16b) was isolated from the leaves of T. dichotoma (84JNP835). [Pg.84]

Tabernaemontana dichotoma (L.) R. Br. ex Roem et Schult. (syn Ervatamia coronaria, E. divaricata, Tabernaemontana coronaria, Rejoua dichotoma) [Apocynaceae]... [Pg.13]

Conophyllidine (548) is identical in all respects with conophylline except for replacement of the epoxide function at positions 14 and 15 of the tabersonine epoxide unit by a double bond (333). Conophylhne has also been subsequently isolated from the South American species, Tabemaemontana glandulosa (336), and from the Thai species, Ervatamia microphylla (in all probabihty T. divaricatd) (337). It has also been reported from another Malaysian species, Ervatamia polyneura (T. dichotoma), under the name polyervine (338). The leaf extract of E. polyneura also yielded the related bisindole, polyervinine (549), which is similar to conophylline, except for the aromatic portion of the vincadifformine unit, which in the case of 549 incorporates an indoline dione chromophore, existing predominantly in its zwitterionic quinoniminium form. [Pg.279]


See other pages where Ervatamia dichotoma is mentioned: [Pg.26]    [Pg.17]    [Pg.19]    [Pg.81]    [Pg.26]    [Pg.17]    [Pg.19]    [Pg.81]   
See also in sourсe #XX -- [ Pg.19 , Pg.81 ]




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