Equipment good practice principles

The principles of Good Laboratory Practice are complied within its laboratory, a Laboratory Policy exists and it is communicated and understood by the laboratory personnel, a sufficient number of qualified personnel, appropriate facilities, equipment, and materials are available in the laboratory and proper training and relevant ... 

Action of proving, in accordance with the principles of good manufacturing practice, that any procedure, process, equipment, material, activity, or system actually leads to the expected result Documented evidence which provides a high degree of assurance that a specific process will consistently produce a product meeting its predetermined specifications and quality attributes and characteristics... 

Dew-point measurement is a primary method based on fundamental thermodynamics principles and as such does not require calibration. However, the instrument performance needs to be verified using salt standards and distilled water before sampling (see Support Protocol). To obtain accurate and reproducible water activity results with a dew-point instrument, temperature, sensor cleanliness, and sample preparation must be considered. Equipment should be used and maintained in accordance with the manufacturer s instruction manual and with good laboratory practice. If there are any concerns, the manufacturer of the instrument should be consulted. Guidelines common to dew-point instruments for proper water activity determinations are described in this protocol. The manufacturer s instructions should be referred to for specifics. 

Process biosafety at the large scale is a mix of good operating practice, reliable and well maintained equipment, and good equipment design. The GOSH principles encapsulate this concept. 

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