1,2-epoxy propane

Epichlorohydrin and 2[Pg.202]

It is not necessary that the intermediate be separated from the reaction medium in the preparation of the end product. Instead, the reaction mixture, after cooling, is treated with 200 ml of water acidified with 42 ml 10% hydrochloric acid solution, and filtered. To the clear, light yellow filtrate is added dropwise a solution of 9.B g (0.07 mol) 5-nltro-2-furaldehyde in 100 ml ethyl alcohol. An orange solution of the hydrochloride results. The free base is precipitated asyellow plates by making the solution basic with saturated sodium carbonate solution. 14 g of the compound is filtered off by suction, washed with alcohol, and dried. The yield, MP 204°C to 205°C (dec.), is 53% of theoretical based on 3-(N-morpholinyl)-1,2-epoxy-propane. Recrystallization from 95% alcohol (75% recovery) raises the melting point to 206°C (dec.). 

Chloro-2,3-epoxy propane See 1-Chloro-2,3-epoxypropane Isopropylamine... 

Synonyms AI3-50540 Allyl alcohol oxide BRN 0383562 CCRIS 1052 EINECS 209-128-3 Epihydric alcohol Epihydrin alcohol l,2-Epoxy-3-hydroxypropane 2,3-Epoxypropanol 2,3-Epoxy-1-propanol Epoxypropyl alcohol Glycide Glycidyl alcohol l-Hydroxy-2,3-epoxy-propane Hydroxymethyl ethylene oxide 2-Hydroxymethyloxiran 3-Hydroxypropylene oxide NCI-C55549 NSC-C55549 Oxiranemethanol Oxiranylmethanol UN 2810. 

Zhang Z, Mo Z, Zhang H, Zhang Y, Na T, An Y, Wang X, Zhao X (2002) Miscibility and hydrogen-bonding interactions in blends of carbon dioxide/epoxy propane copolymer with poly(p-vinylphenol). J Polym Sci, Part B Polym Phys 40 1957-19M... 

A flimUar reaction has now also been reported by PePuy and co-workere,2012 using l -chloro-2-methyls,3-epoxy propane (2-methylepi olilorchydrin) to obtain 1-methylcyclopropaiiol in mnrifT(yt.ft yield. 

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