Epoxide lysis

There are examples in the literature of the formation of epoxides during ozono-lysis of olefins 269... 

Enamines are susceptible to peracid oxidation, presumably through the epoxide, producing the a-hy-droxy ketone after hy lysis. Thus steroidal ketone (88) is converted via the pyrollidino enamine to the a-hydroxy derivative (89) in qiproximately 50% overall yield by treatment of the enamine with MCPBA followed by basic work up. Similar conversion of a steroidal enamide to the a>hydroxy ketone using monoperphthalic acid has been reported. 

Preparation of cross-linked PAN supports has been reported in the literature by Peinemann et al. (2001), when an epoxidized PAN copolymer was subjected to ammono-lysis providing highly solvent stable [including stability in dimethylformamide (DMF)] supports. A highly solvent-resistant UF membrane based on poly(acrylonitrile-co-glycidyl methacrylate) (PANGMA) was reported (Hicke et al., 2002). This membrane was prepared by phase inversion followed by ammonolysis and was also stable in DMF, thus being a very attractive support for preparation of OSN-TFC membranes. 

O. has a long history, is based on RR, uses many modem technologies today (->splitting, - hydrogenation, ->sulfonation, - epoxidation, - ozono-lysis, - alkoxylation and many others), and comprises a huge number of product groups (- fatty... 

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