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Epogen

Anemia may occur in patients with chronic renal failure as tlie result of the inability of the kidney to produce erythropoietin. Erythropoietin is a glycoprotein hormone synthesized mainly in the kidneys and used to stimulate and regulate the production of erythrocytes or red blood cells (RBCs). Failure to produce the needed erythrocytes results in anemia Two examples of drug used to treat anemia associated with chronic renal failure are epoetin alfa (Epogen) and darbepoetin alfa (Aranesp). [Pg.434]

Epoetin-alfa (Epogen, Procrit) Darbepoetin-alfa (Aranesp)... [Pg.983]

EPOGEN Epoetin alfa Amgen also approved and marketed as PROCRIT by Ortho Biotech Anemia associated with chronic renal failure Anemia caused by chemotherapy... [Pg.694]

EPO and colony-stimulating factors Epogen/Procrit, Leukine, Neorecormon, Nespo/Aranesp... [Pg.32]

Epogen (epoetin alfa, rEPO) Anaemia associated with various medical conditions Amgen... [Pg.266]

These plans envision composition-of-matter patents on drug molecules for which development timelines and market potentials can be estimated. Product stories are the clearest, most rational plans because profitable sales can be projected and rNPVs calculated. On the other hand, investors usually perceive higher risks because the rNPVs tend to be dominated by single product candidates for which historical failure rates are high. Examples of product stories include Amgen s development of Epogen and Amylin s development of Symlin. [Pg.588]

Erythropoietins Anemia in kidney and cancer patients Procrit, Eprex, Aranesp, Epogen, NeoRecormon... [Pg.96]

Erythropoietin alpha Epogen/Procrit// Eprex/Erypo Amgen/J J Expired 2012... [Pg.354]

Amgen, in May 2001, was forced to recall its Epogen when counterfeit vials of the product were discovered in the market. Investigation revealed that the counterfeit drug contained only one-twentieth of the labeled strength. [Pg.559]

Johnson Johnson researchers say that they currently have no explanation for this unexpected response to Eprex . Interestingly enough, no similar immune response has been observed with either another of Johnson Johnson s recombinant erythropoietins, Procrit , or with a competitor s comparable product, Amgen s Epogen . [Pg.80]

Epoetin Alfa [Erythropoietin/ EPO] (Epogen/ Procrit) [Recombinant Human Erythropoietin] WARNING Use lowest dose possible may be associated w/1 CV, thromboembolic events /or mortality D/C if Hgb >12 g/dL Uses CRF associated anemia zidovudine Rx in HIV-infected pts, CA chemo -1- transfusions associated w/ surgery Action Induces ery-thropoiesis Dose Adul Peds. 50-150 Units/kg IV/SQ 3x/wk adjust dose q4-6wk PRN Surgery 300 Units/kg/d x 10 d before to 4 d after -I dose if Hct 36% or Hgb, T > 12 g/dL or Hgb t >1 g/dL in 2-wk pmod hold dose if Hgb >12 g/dL Caution [C, +] Contra Uncontrolled HTN Disp Inj SE HTN, HA, fatigue, fever, tach, NA Interactions None noted EMS Monitor ECG for hypokalemia (peaked T waves) t risk of CV thrombotic events OD May cause HA, dizziness, SOB and polycythemia symptomatic and supportive... [Pg.149]

Epogen (rhEPO, produced in a mammalian cell line)... [Pg.502]

Distributed by Amgen Inc (Epogen), Ortho Biotech Products, Raritan, NJ (Procrit)... [Pg.136]

See other pages where Epogen is mentioned: [Pg.42]    [Pg.42]    [Pg.435]    [Pg.385]    [Pg.709]    [Pg.7]    [Pg.8]    [Pg.145]    [Pg.323]    [Pg.405]    [Pg.576]    [Pg.7]    [Pg.40]    [Pg.22]    [Pg.79]    [Pg.339]    [Pg.356]    [Pg.77]    [Pg.170]    [Pg.50]    [Pg.126]    [Pg.72]    [Pg.73]    [Pg.177]    [Pg.132]    [Pg.10]    [Pg.11]    [Pg.270]    [Pg.438]    [Pg.439]    [Pg.7]    [Pg.26]    [Pg.136]   
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Epoetin alfa [erythropoietin, EPO Epogen, Procrit)

Erythropoietin Epogen

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