Epithelial adhesion molecules, renal cell

Went, P., Dirnhoeer, S., Salvisberg, T, Amin, M. B., Lim, S. D., Diener, P. A., Moch, H. (2005). Expression of epithelial cell adhesion molecule (EpCam) in renal epithelial tumors. 

IchimuraT, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cellsafterinjury. J Biol Chem 1998 273 4135-4142. 

Cadherins are a large family of cell-cell adhesion molecules acting in a homotypic, homophilic manner that play an important role in the maintenance of tissue integrity. In the human kidney, several members of the cadherin family (including E- and N-cadherin, cad-herin-6, cadherin-8, and cadherin-11) are expressed in a controlled spatiotemporal pattern. Cadherin-16, also called kidney-specific (Ksp-) cadherin, is exclusively expressed in epithelial cells of the adult kidney. In renal cell carcinomas (RCCs), a complex pattern of cadherin expression is observed. 

Seligson DB, Pantuck AJ, Liu X, et al. Epithelial cell adhesion molecule (KSA) expression pathobiology and its role as an independent predictor of survival in renal cell carcinoma. Clin Cancer Res. 2004 10 2659. 

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