Epilepsy fatty acids

Yuen A. W. C., Sander J. W., Fluegel D., Patsalos P. N., Bell G. S., Johnson T., and Koepp M. J. (2005). Omega-3 fatty acid supplementation in patients with chronic epilepsy A randomized trial. Epilepsy Behavior 7 253-258. 

Bourre JM, Bonneil M. Clement M, Dumont O, Durand G, Lafont H, et al. Function of dietary polyunsaturated fatty acids in the nervous system. Prostaglandins Leukotrienes Essential Fatty Acids 1993 48 5-15. Bridge EM, lob LV. The mechanism of the ketogenic diet in epilepsy. Bull Johns Hopkins Hosp 1931 ... 

David 1. Mostofsky is Professor of Experimental Psychology at Boston University, and holds associate appointments at several major medical institutions in the Boston area. A Charter Fellow of the Academy for Behavioral Medicine Research, he has been active in Behavioral Medicine and Psychopharmacology for many years, and has published numerous articles and books on a variety of topics in this area, especially with regiud to epilepsy, pain, essential fatty acids, and psychoneuroimmunology. He has been the recipient of many awards including, a Marshal Fund Award, Einstein Award, NIH/Fogiuty Fellowship, and a Fulbright Fellowship. 

Valproic acid is an anticonvulsant agent used for the therapy of epilepsy, which occasionally results in hepatotoxicity in young children. The toxicity is characterized by mitochondrial damage, impairment of fatty acid (3-oxidation and lipid accumulation. 

Puri, B.K. 2007. The safety of evening primrose oil in epilepsy. Prostaglandins Leukot. Essent. Fatty Acids 77(2) 101-103. 

R-(-)-GABOB is an inhibitory neurotransmitter24 that has been used in the treatment of human epilepsy.25 It also has hypertensive properties.26 Interestingly, GABOB was first prepared by Tomita in 1923.27 Carnitine is used to treat myocardial ischemia and carnitine deficiency. a it is also important for the transport of long chain fatty acids through the mitochondrial membrane and is used for the treatment of myopathic deficiency.39... 

Newport, M. T. (2010). Caregiver Reports Following Dietary Intervention with Medium Chain Fatty Acids in 60 Persons with Dementia. International Symposium of Dietery Interventions for Epilepsy and other Neurological Diseases. 

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