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Epidermal growth factor receptors irreversible inhibitors

Fry DW. Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy progression from reversible to irreversible inhibitors. Pharmacol Ther 1999 82 207-218. [Pg.334]

Wissner A, Overbeek E, Reich MF et al. Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor-2 (ElER-2). JMed Chem 2003 46 49-63. [Pg.125]

Fry DW, Bridges AJ, Denny WA et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci USA 1998 95 12022-12027. [Pg.125]

Erlichman C, Hidalgo M, Boni JB et al (2006) Phase I study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor, in patients with advanced solid tumors. J Clin Oncol 24 2252-2260... [Pg.185]


See other pages where Epidermal growth factor receptors irreversible inhibitors is mentioned: [Pg.223]    [Pg.399]    [Pg.245]    [Pg.272]    [Pg.648]    [Pg.460]    [Pg.287]   
See also in sourсe #XX -- [ Pg.119 ]




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Epidermal

Epidermal growth factor

Epidermal growth factor , receptor

Factor inhibitor

Growth factor inhibitor

Growth factors receptors

Growth inhibitors

Growth receptor

Irreversible inhibitors

Receptor inhibitors

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