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Eotaxin/CCLll

CCR3 Eosinophils, basophils, activated T-cells (Th2) Eotaxin (CCLll), eotaxin 2 (CCL24), eotaxin 3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), RANTES (CCL6)... [Pg.133]

Cheng SS, Lukacs NW, Kunkel SL Eotaxin/CCLll suppresses IL-8/CXCL8 secretion from human dermal microvascular endothelial cells. J Immunol 2002 168 2887. [Pg.93]

Mariani, M., Lang, R., Binda, E., Panina-Bordignon, P., and D Ambrosio, D. (2004). Dominance of CCL22 over CCL17 in induction of chemokine receptor CCR4 desensitization and internalization on human Th2 cells. Eur. J. Immunol. 34, 231-240. Martinelli, R., Sabroe, I., LaRosa, G., Williams, T. J., and Pease, J. E. (2001). The CC chemokine eotaxin (CCLll) is a partial agonist of the chemokine receptor CCR2b. J. Biol. Chem. 276, 42957 2964. [Pg.98]

CCR3 CCLll, 24, 26 (eotaxin-1, -2, -3) CCL7 (MCP-3) CCL13 (MCP-4) CCL5 (RANTES) No... [Pg.83]

Last but not least, the eosinophil is another important participant in the pathogenesis of asthmatic inflammation and about 80% of the asthma patients show an increased number of eosinophils. Airway epithelial cells are an important source of chemokines and contribute to recruitment of eosinophils to and within the lung. Predominantly, the CCR3 ligand CCLll (eotaxin) attracts and activates eosinophils by acting via the most prominent chemokine receptor on eosinophils CCR3. [Pg.121]

Figure 15.1 CCR3 is expressed on the surface of eosinophils, basophils, mast cells and Th2 lymphocytes, allowing them to respond to the eotaxin family of chemokines (CCLll, CCL24,CCL26) which are implicated in the pathogenesis of allergic inflammation. Figure 15.1 CCR3 is expressed on the surface of eosinophils, basophils, mast cells and Th2 lymphocytes, allowing them to respond to the eotaxin family of chemokines (CCLll, CCL24,CCL26) which are implicated in the pathogenesis of allergic inflammation.
Inhibition of CD26/dipeptidyl peptidase IVenhances CCLll/eotaxin-mediated recruitment of eosinophils in vivo. Journal of Immunology (Baltimore, Md 1950), 181, 1120-1127. [Pg.352]

See other pages where Eotaxin/CCLll is mentioned: [Pg.148]    [Pg.177]    [Pg.355]    [Pg.83]    [Pg.87]    [Pg.89]    [Pg.248]    [Pg.252]    [Pg.273]    [Pg.6]    [Pg.340]    [Pg.353]    [Pg.13]    [Pg.16]    [Pg.17]    [Pg.81]    [Pg.148]    [Pg.177]    [Pg.355]    [Pg.83]    [Pg.87]    [Pg.89]    [Pg.248]    [Pg.252]    [Pg.273]    [Pg.6]    [Pg.340]    [Pg.353]    [Pg.13]    [Pg.16]    [Pg.17]    [Pg.81]    [Pg.224]    [Pg.237]    [Pg.60]    [Pg.416]    [Pg.712]    [Pg.177]    [Pg.1199]    [Pg.85]    [Pg.3]    [Pg.41]    [Pg.224]    [Pg.242]    [Pg.383]    [Pg.340]    [Pg.5]    [Pg.75]    [Pg.150]    [Pg.150]    [Pg.191]   
See also in sourсe #XX -- [ Pg.84 ]

See also in sourсe #XX -- [ Pg.12 ]



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