Enzyme Structure and Mechanism

The active site continues to change until the substrate is completely bound, at which point the final shape and charge is determined [Etters and Anis, 1998). 

---

Fersht, A. Enzyme Structure and Mechanism, 2nd ed. New York W.H. Freeman, 1984. 

T. C. Bruice and S. I Benkovic, Bioorganic Mechanisms, Vol. 1, W. A. Benjamin, New brk, 1966, pp. 1-258 W. P. Jencks, Catalysis in Chemistry and Enzymology, McGraw-Hill, New York, 1969 M. L. Bender, Mechanisms of Homogeneous Catalysis from Protons to Proteins, Wiley-Interscience, New York, 1971 C. Walsh, Enzymatic Reaction Mechanisms, W. H. Freeman, San Francisco, 1979 A. Fersht, Enzyme Structure and Mechanism, 2nd ed., W. H. Freeman, New York, 1985. 

A. Eersht, Enzyme structure and mechanism, W. H. Ereeman and Company, New York 1985. 

Fersht, A. 1985 Enzyme structure and mechanism. New York W. H. Freeman. 

Kisker, C., Schindelin, H. and Rees, D.C. (1997). Molybdenum cofactor - containing enzymes structure and mechanisms. Annu. Rev. of Biochem., 66, 233-267... 

Fersht, A. (1977). Enzyme Structure and Mechanism. W.H. Freeman, New York. Haldane, J.B.S. (1930). The Enzymes. Longmans, Green London. 

A. Fersht (1977) Enzyme Structure and Mechanism, pp. 108-109 175-176, Freeman, Reading. 

---