Environmental applications phosphorous compounds

Gram scale radiolabeled syntheses of these three products were performed using a Mannich-like reaction in which phosphorous acid combines with Carbon-14 labeled formaldehyde and the particular amines required. The environmental application required several millicuries of carbon-14 radioactivity for each phosphonate at specific activities of several millicuries per millimole and high radiochemical purities. We were not successful in producing any of the final products shown in high yields but obtained mixtures containing significant amounts of what appeared to be all the possible intermediate incompletely phosphonated compounds. The separation properties of intermediates and final products were found to... 

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