Enhancer antiaging effect

To date longevity studies have been performed only with (-)-deprenyl, as this compound was the only available synthetic mesencephalic enhancer substance. To illustrate the antiaging effect of (-)-deprenyl, Table 3.8 shows some data taken from our first longevity study on male rats performed between 1984 and 1988. We started the experiments with 2-year-old male rats. Before... 

To further illustrate the peculiar antiaging effect of a synthetic mesencephalic enhancer substance, the results of characteristic human and rat studies are summarized in Figs. 3.21 and 3.22, respectively. 

Table 3.10 shows that (-)-deprenyl, injected subcutaneously three times a week for 18 months, prevented the age-related morphological changes of the pigment granules in the neurocytes of the substantia nigra of rats. This is morphological evidence for the antiaging effect of prophylactic treatment with a synthetic mesencephalic enhancer substance. 

---