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Enhanced, polylactide microspheres

FONG ET AL. Enhancing Drug Release from Polylactide Microspheres... [Pg.215]

Y. Tabata and Y. Ikada, Protein precoating of polylactide microspheres containing a lipophilic immunopotentiator for enhancement of macrophage phagocytosis and activation. Pharm. Res., 6(4), 296-301 (1989). [Pg.122]

In the preparation of microspheres by solvent evaporation from oil-in-water emulsions, the presence of base (NaOH) was found to enhance the release of thioridazine from polylactide micro-spheres. The amount of drug release as a function of time was dependent on the amount of base added to the aqueous phase of the emulsion. Scanning electron micrographs indicate that this increased drug release may be due to modification of the internal structure of the microspheres by sodium hydroxide during fabrication. [Pg.214]


See other pages where Enhanced, polylactide microspheres is mentioned: [Pg.16]    [Pg.36]    [Pg.2332]    [Pg.352]   
See also in sourсe #XX -- [ Pg.214 , Pg.215 , Pg.216 , Pg.217 , Pg.218 , Pg.219 , Pg.220 , Pg.221 , Pg.222 , Pg.223 , Pg.224 , Pg.225 , Pg.226 , Pg.227 , Pg.228 ]




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