Energizing activities

To further illustrate the application of Equation 14.35 (the limiting behavior of the low pressure IE), consider the case when only the external rotations are adiabatic (translations do not contribute to the isotope effect). In this case the ratio of Q s reduces to a ratio of ratios of moments of inertia, which, provided the structure does not change on passing from active molecules to activated complex, is unity. In this simplified example, the isotope effect reduces to a simple ratio of the number of states and state densities in the activated complex and energized (active) molecules for the light (1) and heavy (h) molecules. 

If a sprinkler system is installed in a computer room or similar area, provisions must be made to automatically de-energize all electrical power to the room and equipment, except power to lighting, in the event of sprinkler operation. Ensure that de-energizing activity leads to a fail-safe condition. Preferably, this should take place prior to water application to minimize damage to exposed electronic circuits. This can be accomplished automatically by smoke detection systems. Manual activation is tolerable for constantly attended locations. Where automatic sprinklers are installed in areas containing minimal combustibles as described above, a sprinkler density of 0.10 gpm/ft (0.38 Ipm/m ) should be provided. Refer to NPEA 75. 

The Proton-Motive Force Energizes Active Transport... 

This equation results from the assumption that the actual reaction step in themial reaction systems can happen only in molecules (or collision pairs) with an energy exceeding some tlireshold energy Eq which is close, in general, to the Arrhenius activation energy defined by equation (A3.13.3). Radiative energization is at the basis of classical photochemistry (see e.g. [4, 3 and 7] and chapter B2.5) and historically has had an interesting sideline in the radiation... 

Reaction Rate constant Activation energ)-, kcal/(g-rnol) Frequency factor, rnin ... 

K. McManus, T. Poinsot, and S. Candel. A review of active control of combustion instabilities. Prog. Energ. Combust. Sci., 19 1-29,1993. 

In oriented, partially dehydrated multilayers, under conditions suitable for X-ray diffraction studies, the sarcoplasmic reticulum vesicles retain much of their ATP energized Ca transport activity [200-202], The Ca transport can be initiated by flash-photolysis of P -l(2-nitro)phenyl-ethyladenosine-5 -triphosphate, caged ATP [203-208], The flash-photolysis of caged ATP rapidly releases ATP and effectively synchronizes the Ca transport cycle of the ensemble of Ca -ATPase molecules [190-192,201,209],... 

Chemical modification studies with fluorescein-5 -isothiocyanate support the proximity of Lys515 to the ATP binding site [98,113-117,212,339]. Fluorescein-5 -isothiocyanate stoichiometrically reacts with the Ca -ATPase in intact or solubilized sarcoplasmic reticulum at a mildly alkaline pH, causing inhibition of ATPase activity, ATP-dependent Ca transport, and the phosphorylation of the Ca " -ATPase by ATP the Ca uptake energized by acetylphosphate, carbamylphos-phate or j -nitrophenyl phosphate is only partially inhibited [113,114,212,339]. The reaction of -ATPase with FITC is competitively inhibited by ATP, AMPPNP, TNP-ATP, and less effectively by ADP or ITP the concentrations of the various nucleotides required for protection are consistent with their affinities for the ATP binding site of the Ca -ATPase [114,212,340]. 

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