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Endogenous hyaluronic acid

High-molecular-weight hyaluronic acid is a constituent of normal cartilage that provides lubrication with motion and shock absorbency during rapid movements. Because the concentration and molecular size of endogenous hyaluronic acid decrease in OA, exogenous administration has been studied in an attempt to reconstitute synovial fluid and reduce symptoms. [Pg.29]

The mode of chain initiation in the synthesis of hyaluronic acid is not yet clear. In group A Streptococcus, inhibitors of protein synthesis do not interfere with the synthesis of hyaluronic acid, a result suggesting the absence of polypeptide backbone from streptococcal hyaluronic acid. Although the endogenous hyaluronic acid is bound to membrane(s), it can be separated from the membrane under mild conditions. ... [Pg.436]

Another important consideration when using endogenous polymers is the source of such polymers. Some of them, such as hyaluronic acid and albumin, can already be foimd as recombinant biotechnology products. However, some other polymers, such... [Pg.241]

Hyaluronic acid, or hyaluronan, is a non-sulfated non-epimerized, linear, endogenous glycosaminoglycan existing in vivo as a polyanion of hyaluronic acid and composed of... [Pg.256]

See other pages where Endogenous hyaluronic acid is mentioned: [Pg.160]    [Pg.418]    [Pg.160]    [Pg.418]    [Pg.276]    [Pg.417]    [Pg.283]    [Pg.285]    [Pg.2571]    [Pg.71]    [Pg.1699]    [Pg.211]    [Pg.178]    [Pg.54]    [Pg.233]    [Pg.154]    [Pg.251]    [Pg.428]    [Pg.150]    [Pg.244]    [Pg.249]    [Pg.255]    [Pg.258]    [Pg.178]    [Pg.116]    [Pg.421]    [Pg.917]    [Pg.246]    [Pg.103]    [Pg.242]   
See also in sourсe #XX -- [ Pg.22 ]



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