Endocrine systems occupational exposure

One study that overcomes some of the shortcomings of those just cited reported adverse neurodevelopment outcomes following maternal exposures to 19 organic solvents and mixtures of these. 13 In this study, the women were occupationally exposed to the chemicals listed in Table 24.3. Also included in this table are the K, values and whether or not the specific chemical is a known teratogen or a known endocrine disruptor. 5 It is interesting to note that only three of the chemicals in the study—ethanol, trichloroethylene, and mineral spirits (a mixture of hydrocarbon solvents)—are endocrine disruptors. This shows that teratogenic effects can be induced by chemicals and mixtures that are independent of the endocrine system. 

The relationship between occupational exposure to urban PM and health effects on the endocrine system has been evaluated in several studies (Tomei et al. 2003,2009 ... 

As PCB production increased, more concerns were raised about the health and environmental effects of PCBs, which entered the environment through leakage, production processes, and improper disposal. The persistence and lipophilicity of PCBs resulted in its biomagnification in the environment (see DDT). Problems associated with PCB contamination in wildlife include deformities, tumors, disruption in the endocrine and reproduction systems, and death. Human exposure to PCBs occurs through environmental and occupational routes. The primary exposure... 

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