Enantioselectivity in allylic alkylation

Another conceptually different approach to discriminating the nucleophilic attack at two allyl terminus of symmetrical r) -allyl intermediate was used earlier than those described above [119], As shown in Scheme 8.64, a functional group capable of interacting with nucleophile was connected by a long tether to the one side of chiral diphosphines in order to bring the nucleophile close to only one allyl terminus. For example, chiral ferroceny diphosphines shown in Scheme 8.64 provided fairly high enantioselectivity in allylic alkylation. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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