Enantiomers, separation by capillary electrophoresis

Williams, B.A. and Vigh, G., Dry look at the CHARM (charged resolving agent migration) model of enantiomer separations by capillary electrophoresis,. Chromatogr. A, 777, 295, 1997. 

The capability of quartz microbalances for the analysis of enantiomers has been demonstrated successfully by Bodenhofer et al. [102]. Cyclopeptides have already been successful as chiral selectors in enantiomer separation by capillary electrophoresis [90, 91], Here, we showed that cyclopeptide 1 exhibits different affinities to D- and L-arginine [99], The differences in sensitivity of the quartz microbalances result in a chiral separation factor of 1.12 [76]. Sensitivity differences of the quartz microbalance coated with 1 for the two enantiomers of arginine are shown in Figure 10.13. 

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