Enamines ketocarboxylic acid

If, for example, an a-hydrogen is attached to the carbon atom of the iminium bond, transformation into the corresponding enamine (CXXV) occurs readily, which results in subsequent reaction of CXXV with the starting iminium chloride. Since attack on nitrogen is not possible self-condensation via attack on carbon has been observed, and jS-ketocarboxylic acid amides CXXVI are obtained in good yield... [Pg.88]

An ethereal soln. of the startg. enamine and triethylamine added at -20 to -10° to phosgene, the resulting triethylamine hydrochloride removed by filtration, and the filtrate treated dropwise at -20 to -10° with methanol and triethylamine methyl a-phenyl-/ -pyrrolidinoacrylate. Y 78%. - The reaction of enamines with phosgene occurs under mild conditions and provides reactive intermediates for the synthesis of / -ketocarboxylic acid derivs. and heterocyclics. F. e. and reactions s. A. Halleux and H. G. Viehe, Soc. (C) 1970, 881. [Pg.494]

Ketocarboxylic acid esters from ketones via enamines... [Pg.495]

Addition of enamines to carbon-carbon double bonds d-Ketocarboxylic acid esters from enamines... [Pg.251]

Triethylamine 4(lH)-Pyridazones from a-ketocarboxylic acid chlorides and enamines... [Pg.496]

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