Embossing technology

Martiradonna, L., Carbone, L., De Giorgi, M., Manna, L., Gigli, G., Cingolani, R., and De Vittorio, M. (2006). High Q-factor colloidal nanocrystal-based vertical microcavity by hot embossing technology. Appl. Phys. Lett. 88 181108. 

Having initially demonstrated its power in fabrication of complex microfluidic devices [18-20], hot embossing technologies are now also used to manufacture cell culturing substrates [21,22],... 

Process chain for production of the seat-adjustment switch in hot-embossing technology... 

Correct identification of patients and specimens is a major concern for laboratories. The highest frequency of errors occurs with the use of handwritten labels and request forms. One method for checking identification is to compare identifiers such as the patient s name and his or her unique hospital number. The identification on the specimen label should also correspond with the identification on the requisition form. The use of plastic embossed patient identification cards to imprint the patient s name on test request forms and on blood collection labels can eliminate transcription and identification errors but does not guarantee that tiie patient name on the labels correctly identifies the donor of the specimen. The integration of bar code technology into the analytical systems that are used by clinical laboratories has significantly reduced identification problems (see Chapter 11). 

As an alternative technology, PMMA CE chips fabricated by hot embossing were machined with a triangular tip at the CE channel terminus, to enable MALDI-MS detection by direct contact deposition of the CE effluent onto a rotating ball inlet mass spectrometer (Figure 53.12). The rotating ball acted as a cathode transfer electrode of the sample into the vacuum of the MALDI mass spectrometer, and matrix addition was accomplished in-line, on the surface of the ball. This interface was demonstrated for the CE separation and low fmol MALDI-MS detection of tryptic peptides from 10 nL sample injection volumes. 

A. Kolew, D. Miinch, K. Sikora, and M. Worgull, Hot embossing of micro and sub-micro structured inserts for polymer replication. Microsystem Technologies, 17(4), 609—618, 2010. 

M. Worgull, M. Heckele, and W. Schomburg, Large-scale hot embossing, Microsystem Technologies,... 

M. Worgull, Hot Embossing Theory and Technology of Microreplication, William Andrew, Oxford, U.K., 2009. 

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