Electron Transfer to P450s from Cytochrome

Cytochrome b is a small polypeptide ( 17kDa) containing 134 residues, which are divided into an amino-terminal hydrophilic heme domain and a carboxyl-terminal hydrophobic 

Much of the early data on cytochrome b interactions with P450 has come from in vitro analysis using reconstituted systems. However, the expression in E. insect cells , or yeast  

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