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Electron density maps general observations

Data processing occurs in two stages. Initially, diffraction images are reduced to a tabulation of reflection indices and intensities or, after truncation, structure factors. The second stage involves conversion of the observed structure factors into an experimental electron density map. The choice of how to execute the latter step depends on the method used to determine the phase for each reflection. The software packages enumerated above generally focus on exploitation of anomalous signals to overcome the phase problem for a protein of unknown structure. [Pg.183]


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