Efficient Heterogeneous Catalysis for the Synthesis of a-Aminonitriles

Interestingly, the MC approach for this reaction has been also developed using heterogeneous catalysts such as KjCoWjjO j-SH O [100], supported heteropoly acids [101], montmorillonite [102], sulfuric acid-modified PEG-6000 [103], or organometallic hollow spheres bearing bis(Ai-heterocyclic carbene)-palladium species [104], among others. 

Prakash, Olah, and coworkers developed an efficient strategy using Nafion -H (perfluoroalkanesutfonic acid polymer) and Nafion SAC-13 (10-20% Nafion -H polymer on amorphous silica, porous nanocomposite) as heterogeneous catalysts for one-pot Strecker reaction using aldehydes, ketones, and fluorinated ketones, affording final a-aminonitriles in high yields [64]. 

Recently, Heydari and coworkers have employed dehy-droascorbic acid capped magnetite (DHAA-FejO ) catalyst for the one-pot synthetic approach of synthesis of a-aminonitriles. Final adducts are obtained with high yields employing different aldehydes or ketones and amines. A plausible 

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