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Intestinal permeability effective

Fig. 7.5. The Biopharmaceutics Classification System (BCS) provides a scientific basis for predicting intestinal drug absorption and for identifying the rate-limiting step based on primary biopharmaceutical properties such as solubility and effective intestinal permeability (Pefr). BCS serves as a product control instrument. The BCS divides drugs into four different classes based on their solubility and... Fig. 7.5. The Biopharmaceutics Classification System (BCS) provides a scientific basis for predicting intestinal drug absorption and for identifying the rate-limiting step based on primary biopharmaceutical properties such as solubility and effective intestinal permeability (Pefr). BCS serves as a product control instrument. The BCS divides drugs into four different classes based on their solubility and...
Clinical studies of effective intestinal permeability (Peff), secretion and metabolism of various compounds, such as drugs, environmental pollutants and nutrients are... [Pg.160]

Estimating Effective Intestinal Permeability Coefficient Using a Mass Balance Approach... [Pg.42]

Figure 2.11 A comparison between human and rat effective intestinal permeability coefficients (Peff). The equation describes the correlation for passive diffusion. The inset shows the Peff values in the lower range ( = passive absorption A = carrier-mediated absorption) [46, 47],... Figure 2.11 A comparison between human and rat effective intestinal permeability coefficients (Peff). The equation describes the correlation for passive diffusion. The inset shows the Peff values in the lower range ( = passive absorption A = carrier-mediated absorption) [46, 47],...
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See also in sourсe #XX -- [ Pg.506 ]

See also in sourсe #XX -- [ Pg.535 ]



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