Effect noncooperative

In these molecular type lattices the structure of the CuN402 chromophore is independent of the structure of the host lattice, and the effect is referred to as the noncooperative Jahn-Teller effect.514 It applies to the vast majority of low symmetry copper(II) complexes involving organic type ligands, but even here cooperative effects that influence the ESR properties, such... 

In order to understand the ferromagnetic order that is sometimes found in perovskites containing 3d4 ions, it is necessary to investigate the effect of Jahn-Teller stabilizations when there is no static, cooperative distortion of the entire lattice. Lack of a static Jahn-Teller stabilization may indicate either (1) noncooperative, static distortions or (2) removal of the ground-state degeneracy by resonance between... 

The complexity of the SC membrane hinders such definitive interpretation, but, nevertheless, alterations in endotherms can be used to screen molecules suspected of altering membrane function. Conversely, one should note that the absence of additive-induced alterations in the phase transition profile does not rale out their perturbing effect, but rather indicates that the additive does not modify the gel phase. As described earlier, a DSC thermogram of hydrated but untreated human SC yields four endotherms, the first three of which can be identified as noncooperative lipid-associated phase transitions, while the high-temperature endotheim is attributed to keratin denaturation [33,37]. 

The inhibition of certain enzymes by specific metabolites is an important element in the regulation of intermediary metabolism and most often occurs with cooperative enzymes that are regulated allosterically. Inhibition of enzymes that obey the Michaelis-Menten equation, noncooperative enzymes, is more commonly used by pharmacists to alter a patient s metabolism. Reversible inhibition of noncooperative enzymes is classified into three groups which can be distinguished kinetically and which have different mechanisms and effects when administered. The classes are called competitive, uncompetitive, and noncompetitive inhibition. Mixed inhibition also occurs. In all these types of inhibition, the inhibitor (usually a small molecule) binds reversibly and rapidly with the enzyme. 

The above account of copper(II) stereochemistry and electronic properties (Sections 53,4 and 53.4.4) establishes the uniqueness of the regular octahedral (and trigon octahedral) stereochemistries and the novel temperature variability of this stereochemistry (Sections 53.4.2.li and x) and the corresponding ESR spectra. " In order to understand these properties it is necessary to examine the Jahn-Teller theorem in a little more detail, as the consequences of this theorem extend beyond the above two topics and will cover the following (i) temperature variable (fluxional) copper(II) pseudo stereochemistries (ii) non temperature variable, static copper(II) stereochemistries (iii) the plasticity effect and varying tetragonal distortions (iv) the second order Jahn-Teller effect " and (v) the cooperative" and noncooperative " Jahn-Teller effects. For this reason the application of the Jahn-Teller theorem to the coordination chemistry of the copper(II) ion will be described" " and extended to the above topics." " " ... 

Strictly taken, a prerequisite for the discussion of cooperativity or nonadditivity requires the definition of the additive or noncooperative case [50]. Generally, in the field of intermolecular interaction, the additive model is a model based on the concept of pairwise additive interactions. For atomic clusters per definition, but also for molecular clusters, the use of pairwise additive interactions is almost always used in combination with the assumption of structurally frozen interaction partners. Even in cases of much stronger intermolecular interactions the concept of pair potentials modified to that of effective pair potentials is often used. Most of the molecular dynamics calculations of liquids and molecular solids take advantage of this concept. 

The Noncooperative Model, (a = 7 = 1, c= 0). This model applies to assembhes that involve only intemiolecular interactions without any allosteric effect. The occupation of the various binding sites of the receptor is dictated only by statistics. This model is the reference for spotting the presence of allosteric effects in real systems. It also applies to the formation of a given ohgomer in isodesmic polymerizations. This process is exemplified by a monomer A—B that undergoes a reversible polymerization in which all of the stepwise association constants are identical and equal to K. The formation constant of each oligomer (A—B), is given by Eq. [51] in which a = y = 1, c = 0, = 1 and f) = 1 -... 

Kumar, M. V. (2011). Are joint ventures positive sum games The relative effects of cooperative and noncooperative behavior. Strategic Management Journal, 32(1), 32-54. 

This gap is an artifact of the simple-cubic lattice and the resulting excitation transition is a noncooperative effect Consider a cuboid conformation with a chain end located in one of the comers. It forms two energetic contacts with the nearest neighbors nonadjacent within the chain. Performing a local off-cube pivot-rotation of the bond the chain end is connected with, these two contacts are lost and none new is formed. 

Noncooperative systems have the property that the binding of multiple ligands to the same protein are independent the binding of one ligand has no effect on the affinity of subsequent ligands. In this case, the fraction of protein with ligand bound, or the fractional saturation (Y), can be defined as in... 

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