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Early development HPLC gradient elution

Weller et al. [43] described an early high throughput UV-triggered HPLC purification system to support the parallel synthesis efforts at Bristol-Myers Squibb. This open-access instrument used fast flow rates and rapid universal reverse-phase gradient elution methods that enabled the purification of up to 200 samples per day at weights up to 200 mg/sample in an unattended mode. Customized software and hardware were developed for this system to optimize efficiency and throughput. [Pg.194]

See other pages where Early development HPLC gradient elution is mentioned: [Pg.171]    [Pg.171]    [Pg.246]    [Pg.438]    [Pg.170]    [Pg.814]    [Pg.72]    [Pg.768]    [Pg.268]    [Pg.1033]    [Pg.696]    [Pg.153]    [Pg.3359]   


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