Dysthyroidisms

Mekkakia-Benhabib C, Marcellin P, Colas-Linhart N, Castel-Nau C, Buyck D, Erlinger S, Bok B. Histoire nat-urelle des dysthyroidies survenant sous interferon dans le traitement des hepatites chroniques C. [Natural history of dysthyroidism during interferon treatment of chronic hepatitis C.] Ann Endocrinol (Paris) 1996 57(5) 419-27. 

Cant JS, Wilson rM.The ocular and orbital circulations in dysthyroid ophthaknopathy.Trans Ophthalmol Soc UK 1974 94 416-429. 

Trobe JD, Glaser JS, Laflamme P. Dysthyroid optic neuropathy. Clinical profile and rationale for management. Arch Ophthalmol 1978 96 1199-1209. 

Dysthyroidism due to amiodarone comparison of spontaneous reporting in Aquitaine, Midi-Pyrenees and Languedoc-Roussillon. [Inter-regional differences in dysthyroidism due to amiodarone comparison of spontaneous notifications in Aquitaine, Midi-Pyrenees and Languedoc-Roussillon.] Therapie 2001 56(3) 301-6. 

Benelhadj S, Marcellin R Castelnau C, et al. Incidence of dysthyroidism during interferon therapy in chronic hepatitis C. Horm Res 1997 48 209-214. 

Improper or excessive use of detergents Side effects of drugs By internal cause Pruritus senilis Psychosomatic pruritus Delusions of parasitosis Biliary stasis Diabetes mellitus Uremia Pregnancy Dysthyroidisms Cancers... 

Dysthyroid endocrine orbitopathy (EO) or thyroid eye disease is the most common disorder affecting the orbit, usually presents in middle-aged women, and represents the most frequent cause of unilateral or bilateral proptosis in adults (Mueller-Forell and Pitz 2004 Aviv and Miszkiel 2005). EO is predominantly associated with autoimmune hyperthyroidism, which is also referred to as Morbus Basedow or Grave s disease (Mueller-Forell and Pitz 2004), but the orbitopathy may precede thyroid disease or occur with euthyroid or hypothyroidism (Aviv and Miszkiel 2005). EO is associated with edema of all structures of the orbit. The hallmarks of EO, however, are spindle-shaped edema of the intra-orbital muscles, which leaves out the tendons, and enlargement of the intra-orbital fat tissue (Fig. 12.7) (Mueller-Forell and Pitz 2004 Aviv and Miszkiel 2005). Muscular edema usually is most pronounced in... 

With the exception of iodine-containing ones, no drug is known to be the cause of hyperthyroidism, The mechanisms by which some drugs, others than iodine-containing ones, provoke hypothyroidism are relatively well documented (36) In this section, we will briefly discuss dysthyroidism as a result of iodine contamination, stressing the role of XRF measurements in its detection. ... 

AMIODARONE INDUCED DYSTHYROIDISM HYPOTHYROIDISM FOLLOWED BY HYPERTHYROIDISM... 

Amiodarone, an anti-arythmic drug containing 37.2 % of organic iodine, may induce hypothyroidism and hyperthyroidism. Dysthyroidism can occur during treatment, but also many months after its discontinuation in patients with underlying thyroid disorders, as well as in subjects with apparently normal glands. We report the case of a patient who developed hypothyroidism followed by hyperthyroidism, related to amiodarone therapy. 

The pathogenesis of amiodarone induced dysthyroidism is discussed defective intrathyroidal autoregulation due to the high iodine level does not seem sufficient to explain hypothyroidism and h5q)erthyroidism in the same patient. Alternative explanations could be autoimmune phenomenas and genetic predisposition. 

Metathyroidism.—Production of abnormal secretions of the gland may complicate many varieties of Graves s disease and toxic adenomata of the gland. The condition is sometimes termed thyrotoxicosis, toxic goitre, and dysthyroidism. The chief... 

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