Dynamic nuclear polarization solution-state

Membranes and model membranes exhibit liquid crystalline behavior and this has been exploited in a number of studies to obtain valuable information on the structure and dynamics of membrane associated peptides and proteins as well as on the interaction of the peptides with the membranes themselves. NMR spectroscopy of nuclei such as proton, carbon, deuterium, nitrogen and phosphorus has been utilized for such purposes. Structure elucidation of membrane-associated peptides and proteins in oriented bilayers by solid-state NMR spectroscopy has been reviewed. A survey on the use of static uniaxially oriented samples for structural and topological analysis of membrane-associated polypeptides is available. The theoretical background has been dealt with and a number of examples of applications provided. In addition, ongoing developments combining this method with information from solution NMR spectroscopy and molecular modelling as well as exploratory studies using dynamic nuclear polarization solid-state NMR have been presented. The use of N chemical shift anisotropy, dipolar interactions and the deuterium quadrupolar split-... 

Abstract Solution-state dynamic nuclear polarization (DNP) is an increasingly... 

It is my pleasure to introduce Volume 73 of Annual Reports on NMR. In common with previous volumes, it contains reports from a few of the many areas of NMR active research. The first contribution is by T. W. T. Tsai and J. C. C. Chan on Recent Progress in the Solid-State NMR Studies of Biomineralization the topic Recent Advances in the NMR Spectroscopy of Chlorine, Bromine and Iodine is covered by B. J. Butler, J. M. Hook and J. B. Harper M. D. Lingwood and S. Han report on Solution-State Dynamic Nuclear Polarization the topic of Solid-State NMR of Membrane Proteins Moving Towards Greater Complexity is covered by L. K. Thompson Chromatographic NMR is the topic chosen by S. Caldarelli the final contribution on Kinetic Monte Carlo Simulation of DNMR Spectra is by Z. Szalay and J. Rohonczy. My grateful thanks are due to all of these reporters for their interesting and timely contributions. 

The seminal work of Marcus and Hush has had a significant impact on the development of PET. Pioneering efforts by Sutin, Hopfield, Jortner, and others established the connection between thermal electron transfer and photoelectron transfer [6]. This work set the stage for a notable series of experiments where laser flash spectroscopy [7], chemically induced nuclear polarization [8], resonance Raman spectroscopy [9], time-resolved microwave conductivity [10], and time-resolved photoacoustic calorimetry [11], to site only a few examples, have been successfully employed to chart the dynamics of PET in homogeneous solution, the solid-state, and organized assemblies. 

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