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Dynamic Approaches towards Catalyst Discovery

Patrizia Calzercmo, Ciulio Casparini, Marta Dal Molin, and LeonardJ. Prins [Pg.221]

Comprehen ve Enantioselective Organocakdy s Cakdysts, Reactions, and Applications, First Edition. [Pg.221]

The superb interplay between functional groups in the active site of enzymes, the substrate, and the transition state has led chemists to propose artificial systems able to mimic (at least part of) these recognition events [11, 12]. Such supramo-lecular systems have served as model systems to explain phenomena observed in enzymes and have permitted very detailed studies that have contributed to a mechanistic understanding of the reaction pathways involved. Although occasionally catalytic efficiencies have also been obtained that come close to the values of the natural counterparts, as a general rule the artificial systems do not live up to [Pg.222]


Gasparini G, Dal Molin M, Prins LJ (2010) Dynamic approaches towards catalyst discovery. Eur J Org Chem 2429-2440... [Pg.103]


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Catalyst approaches

Catalyst discovery

Catalyst dynamics

Discovery, approaches

Dynamic approach

Dynamic catalyst discovery

Dynamical approaches

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