Dyes, antineoplastic

Mithramycin is used as a DNA binding fluorescent dye, as an antineoplastic agent, and to reduce hypercalcemia, especially due to malignancies. Mithramycin is a potent inducer of fetal hemoglobin production in erythroid cells and is being... 

USE Insect chemosterilant in dyeing, creaseproofing and flameproofing textiles stabilizer for polymers in photographic emulsion hardening. therap cat Antineoplastic. 

Azo dyes are known for their medicinal importance and are widely recognised for their use in several therapeutic areas including antineoplastics [42], antidiabetics [43], antiseptics [44], antibacterial [45] and antitumour [18]. They are known to be involved in a number of biological reactions such as the inhibition of deoxyribonucleic acid (DNA), ribonucleic acid, protein synthesis, carcinogenesis and nitrogen fixation... 

Albumin, a major constituent in serum (60-80 mg/L), is known to act as a transport carrier for small proteins. Also, many antineoplastic drugs bind to albumin, often at the 80-95% level. Removal or depletion of albumin is a major problem there are problems with ultrafiltration (e.g., membrane binding of small proteins and drugs) and other approaches, e.g., Cibacron dye columns and immunoaffinity-based protein subtraction chromatography. Albumin removal using acetonitrile may be a simple alternative [54] however, there is no truly satisfying method at this time. 

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