Duretter

Chapman KT, Kopka IE, Durette PI, Esser CK, Lanza TJ, Izquierdo-Martin M, Niedzwiecki L, Chang B, Harrison RK, Kuo DW, Lin T-Y, Stein RL, Hagmann WK. Inhibition of matrix metalloproteinases by N-Carboxyalkyl peptides. J Med Chem 1993 36 4293-4301. 

Beveridge, I. and Durette-Desset, M.C. (1994) Comparative ultrastructure of the cuticle of trichostrongyle nematodes. International Journal for Parasitology 24, 887-898. 

Durette-Desset, M., Gasser, R.B. and Beveridge, I. (1994) The origins and evolutionary expansion of the Strongylida (Nematoda). InternationalJournalfor Parasitology 24,1139-1166. 

SCHEME 9. Durette, Hough, and Richardson s synthesis of methyl 3-bromo-3-deoxy-p-maltoside via opening of the 2,3-allo-epoxide derived from the l,2,2, 3, 4, 6,6 -heptaacetate of methyl p-maltopyranoside (1974). 

Richardson and Hough s efforts on the chlorination of sucrose ran in parallel with their studies on the selective chlorination of other readily available disaccharides. One notable piece of work done with Philippe L. Durette involved a study of the regioselective chlorination of methyl (S-maltoside (Scheme 31), which was undertaken with the long-term objective of possibly developing a future synthesis of the natural antitumor agent, amicetin. 

In Durette s study, he treated methyl (S-maltoside with an excess of sulfuryl chloride at low temperature in chloroform-pyridine and thereafter warmed the mixture to room temperature. After dechlorosulfation with a catalytic amount of sodium iodide in methanol and O-acetylation, the stereochemically inverted 4,6,3 6 -... 

SCHEME 31. Durette, Hough, and Richardson s study of the selective chlorination of methyl p-maltoside with sulfuryl chloride (1973). 

P. L. Durette, L. Hough, and A. C. Richardson, The chemistry of maltose. Part 1. The reaction of methyl a-maltoside with sulphuryl chloride, Carbohydr. Res., 31 (1973) 114—119. 

Durette, P., Kopka, I., MacCoss, M., Mills, S., (Merck Co.) Heteroaryl spiroethercycloalkyl tachykinin receptor antagonists, EP 5929094 (1999). 

P. L. DURETTE, D. HORTON, and J. D. WANDER The Ohio State University, Columbus, Ohio 43210... 

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