DSSTox database network

Richard, A.M. and Williams, C.R., Distributed Structure-Searchable Toxicity (DSSTox) database network a proposal, Mutation Res., 499, 27-52, 2002. 

The Distributed Structure-Searchable Toxicity (DSSTox) Database Network is a public database containing more than 1000 molecules annotated with toxicity data. The database can be searched online. The chemical structures can also be downloaded from the web site for analysis (vide infra). 

US EPA (2008). Distributed Structure-Searchable Toxicity (DSSTox) Database Network, Vol. 2008. Vogt, A., and Lazo, J. S. (2007). Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases. Methods 42, 268-277. 

A second initiative is being developed by Dr. Ann Richard and coworkers at the EPA. The Distributed Structure-Searchable Toxicity (DSSTox) public database network is a flexible community-supported, web-based approach for the collation of data. It is based on the SDF format for the representation of chemical structure. It is intended to enable decentralized, free public access to toxicity data files. This should allow users from different disciplines to be linked. Public, commercial, industry, and academic groups have also been asked to contribute to, and expand, the DSSTox public database network. Data from potentially any toxicological endpoint can be collated in the DSSTox public database network, including both human health, and environmental endpoints (Richard et al 2002 Richard and Williams, 2002). 

EPA. (2005b), DSSTox Public Database Network. Accessed online at http //www.epa.gov/ nheerl/dsstox/... 

Richard AM, Williams CR. Distributed structure-searchable toxicity (DSSTox) public database network A proposal. Mutat Res 2002 499 27-52. 

Distributed Structure-Searchable Toxicity (DSSTox) public database network by the US EPA, as well as GeneTox and ECOTOX [28],... 

DSSTox Distributed Structure-Searchable Toxicity Database Network. Distributed toxicity databases, which is focused on structure search, upload and the standardization of the structural information associated with toxicity data http //www.epa. gov/ncct/dsstox/index.html... 

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