Drying equipment batch fluid beds

The fluid bed processor was used as an efficient way to dry a product due to suspension of particles in the hot air stream. However, over the last 35 years, the development in the pharmaceutical industry and the proliferation of the batch fluid bed processing technology in other industries as food, polymer, detergent, etc., has provided the opportunity to use the batch fluid bed processor for granulation, coating of particles, and pelletization. The advances in the fluid bed can be attributed to several factors. The needs of formulators, the requirements of the regulators, and technological innovations from the manufacturers of these equipments are... 

In conclusion, drug A production was shown to be within established specifications, and there is no reason to believe this will not be the case for future production as long as all practices are continued in their present form. Furthermore, there is no significant difference between batches produced by the tray dryer process and the fluid bed process. A validation report should memorialize these findings. The report should also recommend eliminating the option to use a no. 5 screen for the wet milling step and a no. 12 screen to pulverize the dried granulation. There is no experience or only limited experience with this equipment that supports its continued availability. In the same vein, the final blend time should be standardized at 10 min and automatically controlled by means of a timer. 

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