Drugs engineering design

Vauthier C, Fattal E, Labarre D (2004). From polymer chemistry and physicochemis-try to nanoparticulate drug carrier design and applications. In Yaszemski M J, Trantolo D J, Lewandrowski K V, et al. (eds.). Tissue Engineering and Novel Delivery System Marcel Dekker, New York, pp. 562-598. 

SUMMARY AND FUTURE OUTLOOK SYNTHONIC ENGINEERING PARTICLE PASSPORT AND THE FUTURE OF THE DRUG PRODUCT DESIGN... 

Jones, D. S., et al. (2012). Novel semi-interpenetrating hydrogel networks with enhanced mechanical properties and thermoresponsive engineered drug delivery, designed as bioactive endotracheal tube biomaterials. European Journal of Pharmaceutics and Biopharmaceutics, 52(3), 563-571. 

Aqvist J, C Medina and J-E Samuelsson 1994. A New Method for Predicting Binding Affinity Computer-aided Drug Design. Protein Engineering 7 385-391. 

What can be done by predictive methods if the sequence search fails to reveal any homology with a protein of known tertiary structure Is it possible to model a tertiary structure from the amino acid sequence alone There are no methods available today to do this and obtain a model detailed enough to be of any use, for example, in drug design and protein engineering. This is, however, a very active area of research and quite promising results are being obtained in some cases it is possible to predict correctly the type of protein, a, p, or a/p, and even to derive approximations to the correct fold. 

A. K. Dillow and A. M. Lowman (eds.), Biomimetic Materials Design, Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery, Marcel Dekker, New York, 2002. 

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