Drug Transport Mediated by SLC Transporters Using Eukaryotic Cells

Drug Transport Mediated by SLC Transporters Using Eukaryotic Cells 

HEK293 cells are perfectly used to express and study liver specific uptake transporters like organic anion transporting polypeptides (OATPs). One should consider the endogenous expression of OATs if using HEK293 cells for the kidney specific uptake transporter. In these cases transfection of CHO (Chinese hamster ovarian) cells might be preferred. 

Brewer CB (1994) Cytomegalovirus plasmid vectors for permanent lines of polarized epithelial cells. Methods Cell Biol 43 Pt A 233-245 

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II.I.2.1 Drug Transport Mediated by SLC Transporters Using Eukaryotic Cells 532... 

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