Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Drug target screening

An NMR screening strategy in which a small but diverse set of small molecules is screened against a potential drug target was recently described... [Pg.20]

Despite the complexity of the experiments and the enormous data manipulation necessary, complex biological pathways, as well as new drug targets are being identified by this method. Examples include screens for compounds that arrest cells in mitosis, that block cell migration, and that block the secretory pathway [50], or assays with primary T cells from PLP TCR transgenic mice for their inhibitory activity on the proliferation and secretion of proinflammatory cytokines in PLP-reactive T cells [51], and identification of small-molecule inhibitors of histone acetyltransferase activity [52]. [Pg.49]

Kinases remain a highly pursued drug target for numerous therapeutic areas [95]. In addition to the primary screen, selectivity profiling of... [Pg.422]

Receptorome Screening to Identify Drug Targets and Antitargets... [Pg.144]

See other pages where Drug target screening is mentioned: [Pg.264]    [Pg.3041]    [Pg.40]    [Pg.426]    [Pg.264]    [Pg.3041]    [Pg.40]    [Pg.426]    [Pg.57]    [Pg.58]    [Pg.364]    [Pg.917]    [Pg.6]    [Pg.40]    [Pg.10]    [Pg.145]    [Pg.127]    [Pg.150]    [Pg.223]    [Pg.65]    [Pg.66]    [Pg.2]    [Pg.163]    [Pg.47]    [Pg.39]    [Pg.48]    [Pg.144]    [Pg.339]    [Pg.341]    [Pg.170]    [Pg.1]    [Pg.334]    [Pg.369]    [Pg.370]    [Pg.10]    [Pg.317]    [Pg.257]    [Pg.89]    [Pg.133]    [Pg.158]    [Pg.192]    [Pg.139]    [Pg.282]    [Pg.194]    [Pg.207]    [Pg.417]    [Pg.418]    [Pg.419]    [Pg.72]   
See also in sourсe #XX -- [ Pg.40 ]



SEARCH



Drug Screens

Drugs screening

Drugs targeting

Screening target

Targeted drugs

© 2024 chempedia.info