Drug-taking behaviors

Griffiths. R.R. Bigelow, G.E. and Heimingfield, J.E. Similarities in animal and human drug taking behavior. In Mello, N.K., ed. Advances in Substance Abuse Behavioral and Biological Research. Greenwieh JAI Press, 1980. pp. 1-90. 

Meil and See 1996 Self and Nestler 1988 Stewart 1983), and may become critical determinants of reinforcement of drug-taking behavior by nicotine administration. 

Harvey DM, Yasar S, Heishman SJ, PanliUo LV, Henningfield JE, Goldberg SR (2004) Nicotine serves as an effective reinforcer of intravenous drug-taking behavior in human cigarette smokers. Psychopharmacology 175 134-142... 

Some of this difference in outcomes can be attributed to differences in metabolism—how the drug is absorbed, distributed in the body, chemically converted, and excreted. Thus two persons with the same body weight can consume the same number of drinks and have different blood alcohol levels two hours later. For more subtle and less known reasons, the effectiveness of the drug in creating its effects and in reinforcing drug-taking behavior also varies. 

Substance abuse is defined by maladaptive patterns of drug-taking behavior that produce symptoms to indicate that the individual continues use of the substance despite significant substance-related problems [9], The goal of preclinical abuse liability evaluations is to predict the likelihood that some drug will maintain these maladaptive patterns of drug-taking behavior in a... 

Kales et al. (1991), in a placebo-controlled sleep lab study, showed that even under brief, intermittent administration and withdrawal of triazolam (and, to a lesser extent, temazepam), patients experienced rebound insomnia, thereby predisposing to drug-taking behavior and increasing the potential for drug dependence. ... 

Use of the DSM-IV Drug Tolerance, Withdrawal, and Drug-Taking Behavior... 

Having a clear and specific pattern of drug-taking behavior... 

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