Drug initiation

Drug Initial Daily Dose Target or Maximum Daily Dose Monitoring... 

Hemodynamic parameters should be routinely monitored to assess drug tolerance. Assess blood pressure at baseline, after drug initiation and dose titration, then periodically thereafter in patients treated with fk-blockers, CCBs, nitrates, ACE inhibitors, and/or ARBs. 

Liposomes are membrane-based supramolecular particles that consist of a number of concentric lipid membrane bilayers separated by aqueous compartments (Figure 13.15). They were developed initially as carriers for therapeutic drugs. Initially, the bilayers were almost exclusively phospholipid based. More recently, non-phospholipid-based liposomes have been developed. 

Drug Initial dose (mg/day) Dose range (mg/day) Active metabolite Comment... 

Ferrendelli JA. Concerns with antiepileptic drug initiation Safety, tolerability, and efficacy. Epilepsia 2001 42 28-30. 

Drug initiation risks of children of parents with drug problems... 

Proliferating Problems Exposure to Drugs and Drug Initiation... 

PROLIFERATING PROBLEMS. EXPOSURE TO DRUGS AND DRUG INITIATION / 123... 

It is as important to consider the reasons why young people living in intimate proximity to drugs turn away from them as it is to think about their vulnerability to drug initiation. This is underlined by the fact that most of the children and young people interviewed for both of the research projects reported here, did not, at least at that time, go on to develop drug problems. 

Expect leukopenia to resolve in 17-28 days. Anemia generally occurs after large doses or prolonged therapy. Thrombocytopenia may occur 10-15 days after drug initiation. 

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