Drug formulations long-acting

Drug formulations Long-acting injectable risperidone is commonly used in patients with psychoses. There have been two studies sponsored by Janssen Cilag, the risperidone marketing authorization holder. In the first, an observational study in 842 individuals (mean age 41 years), 27% had withdrawn after 6 months because of adverse events (mean dose at end-point 36 mg) [129 ]. 

Depot injection A long-acting formulation of an antipsychotic drug given by occasional (often monthly) intramuscular injection. 

Q34 For which of the following drugs is a long-acting oral formulation available ... 

TABLE 6-5. Drug delivery systems of long-acting stimulant formulations ... 

Sulfadoxine is the only long-acting sulfonamide currently available in the United States. Urinary excretion—especially of the free form—is very slow, resulting in prolonged drug levels in serum. Sulfadoxine is available only as Fansidar, a combination formulation with pyrimethamine, which is used as a second-line agent in treatment for malaria (Chapter 53 Antiprotozoal Drugs). 

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