Drug Delivery System by Grafted Polysaccharides

Graft copolymers are used as matrix tablets for prolonged-release of drugs via oral mode, due to its simple and low-cost manufacturing process. It is important to maintain the therapeutic level of any drug which is administered in the body for treatment. Therapeutic level refers to the concentration of drug in the body tissues, blood, etc., without causing any side effects. [Pg.464]

Conventional delivery systems (CDS) are characterized by rapid and uncontrolled drug release kinetics. Here, drug absorption is controlled by the physiological mechanisms which assimilate the therapeutic molecule [53,54]. [Pg.464]

Controlled release system (CRS) consists of the drug enclosed in a matrix, which releases it at a predetermined rate. Thus the therapeutic level of drug is also [Pg.464]

Basically, there are three basic modes of drug delivery [Pg.465]

Targeted delivery or spatial distribution of drug It has the goal of delivering the drug to specific cells, tissues or organs [55]. [Pg.465]

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