Drivers for Performing Azo Chemistry in Micro Reactors

Diazo coupling was used to demonstrate the feasibility of organic multi-step synthesis on a chip [4]. This involved showing the safe quenching of hazardous intermediates such as the diazonium salts needed as precursor for that synthesis. Especially, this involves the in situ generation and consumption of such species. 

From an analytical point of view, azo coupling is easy to monitor as visual inspection of the color formation by reaction in transparent reactors can be performed. 

Coupled with the latter investigations, it was shown that a diazo suspension can be fed through a micro device without leading to plugging [55]. This broadens the scope of micro processing applicability towards azo pigment formation. 

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