DRIE

An example of a stereoselective hydrogenation in ionic liquids was recently successfully demonstrated by Drie en-H6lscher et al. On the basis of investigations into the biphasic water/n-heptane system [51], the ruthenium-catalyzed hydrogenation of sorbic acid to cis-3-hexenoic acid in the [BMIM][PFg]/MTBE system was studied [52], as shown in Scheme 5.2-8. 

Fig. 2.70 Micro-channel array formed by silicon DRIE. Reprinted from Kandlikar and Grande (2002) with permis-...

One way to fabricate such a reactor is by deep reactive ion etching (DRIE) with a time-multiplexed inductively coupled plasma etcher (most details on fabrication are given in [77]) [7, 77, 78]. Regions of major importance such as the retainers are etched through to avoid differences in stmctural depth which may cause uneven flow. To generate various channel depths in one design, both front-side and back-... 

The device was realized by deep reactive ion etching (DRIE) using the SU-8 technique, producing vertical side walls [72-74]. This fabrication route was chosen to avoid crystallization, which is known to occur at sharp channel edges. Using DRIE smooth, curved corners can be realized, unlike by conventional silicon wet etching. 

Van Drie J (2006) Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26—30, 2006... 

J. H. van Drie, Strategies for the determination of pharmacophoric 3D database queries,... 

Use chunky dehydrating agents like anhydrous calcium sulfate (Drie-rite). Chunky drying agents have a much smaller surface area, so not much of the product gets adsorbed. 

Schematic of the Si-nMEA fabrication process (a) sputter Au layer on double-side polished wafer (b) pattern Au layer with liftoff process (c) spincoat and cure a polyimide layer (d) perform the double-sided photolithography to pattern etch pits (e) etch Si in ICP-DRIE to form Au/Si electrode (f) dice the wafer into a single die (g) RIE etch the polyimide layer with a shadow mask to expose current collecting region (h) electroplate Pt black on Au layer (i) sandwich both electrodes with Nafion 112 in a hot-press bonder. (Reprinted from J. Yeom et al. Sensors Actuators B107 (2005) 882-891. With permission from Elsevier.)...

DRIE to define fluidic ports (top), channels end release pits (bottom)... 

Van drie, J.H., Weininger, D., and Martin, Y.C. ALADDIN an integrated tool for computer-assisted molecular design and pharmacophore recognition from geometric, steric, and substructure searching of three-dimensional molecular structures./. Comput.-Aided Mol. Des. 1998, 3, 225-251. 

Drs. P. Acklin, R. Amstutz, D. Bojanic, B. Faller, P. Fuerst, R. Lewis, A. Marzinzik, C. McCarthy, F. Petersen, J. Priestle, L. Urban, H.-J. Roth, U. Schopfer, J. Tallarico, R. Tommasi, J. Van Drie, J. Zimmermann (all NIBR associates) are acknowledged for various support and discussions. 

Van Drie, J. H. and Lajiness, M. S. (1998) Approaches to virtual library design. Drug Discovery Today 3, 274-283. 

Drie, J. H. (2005) Pharmacophore-based virtual screening a practical perspective, in (Alvarez, J., Shoichet, B., eds.) Virtual Screening in Drug Discovery. CRC Press, Boca Raton, FL, pp. 157-205. 

Another receipt for Starres. Take of saltpeter one pound, gunpowder and brimston of each halfe a pound these must be mixed together, and of them make a paste, with a sufficient quantity of oil of peter (petroleum), or else of faire water of this paste you shal make little balles, and roll them in drie gunpowder dust then dry them, and keepe them for your occasions.3... 

---