Draper investigation

The choice of an appropriate experimental design depends on the experimental circumstances. Box and Draper [12] (p. 502, 305) list a series of experimental circumstances that should be considered by the investigator when selecting a response surface design. Many of these considerations also apply to split-plot designs, and to experimental design in general. 

Holland, A. C., and J. S. Draper, 1967. Analytical and experimental investigation of light scattering from polydispersions of Mie particles, Appl. Opt., 6, 511-518. 

Several RNA systems are capable of folding/binding in the absence of Mg2+ and such systems have been the focus of recent investigations (Lambert et al., 2009). These studies have identified intriguing dependencies of RNA stability on monovalent counterion type that have merited closer scrutiny through computational methods. An elegant example is the Tar-Tar kissing-loop system studied by Draper and coworkers (Lambert et al,... 

Draper D. S. and Johnston A. D. (1992) Anhydrous P-T phase relations of an Aleutian high-MgO basalt an investigation of the role of olivine-liquid reaction in the generation of arc high-alumina basalts. Contrib. Mineral. Petrol. 112, 501-519. 

This reaction was first thoroughly investigated by Bunsen and Roscoe in 1855 (Ostwald s Klassiker, 34 and 38) It had, of course, been the subject of earlier work, the most important conclusion of such work being the statement known as the Grotthus-Draper Absorption Law, vtz only those rays are effective which are absorbed Draper had also made the extremely interesting observation that chlonne which had been exposed to light had somewhat different properties from unexposed chlorine, in that the previously exposed chlonne reacted much more rapidly with... 

Extensive experiments have been carried out on aging rodents to determine the effect on bone loss of those dietary factors of possible importance in the etiology of human osteoporosis calcium, phosphorus, protein, fluoride. The results of these studies have been reviewed elsewhere (Draper, 1985 Yuen et al, 1984) and will be only briefly summarized here. Investigation of the possible role of vitamin D in bone loss in rodents is precluded by their low requirement for this vitamin. 

Box and Draper warn, however, that the investigator should not resort immediately to the joint analysis of responses. Rather he should. .. consider the consistency in the minima of individual and combined (the minors of V) responses. Yet a formal lack of fit test has not been proposed. 

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