Double stranded RNA binding motif

DSRM Double-stranded RNA binding motif E(MFP)B 2(2) 12(19) 1STU... 

Tian, B., Bevilacqua, PC., Diegelman-Parente, A., Mathews, M.B. The double-stranded-RNA-binding motif Interference and much more. Nat. Rev. Mol. Cell Biol. 2004, 5,1013-23. 

Hairpins can form when there are complementary sequences within the same strand but separated by a noncomplementaiy region, such as the sequence 5 -CGCGCGCGAAAGCGCGCG-3 where the central GAAA forms the loop and the imderlined bases at the termini form the stem (Fig. 5). If a hairpin is formed within the context of double-stranded DNA, the complementary strand can also fold into a hairpin, yielding a cruciform structin-e, or remain impaired. Such structures likely serve as binding sites for proteins. Fimthermore, the hairpin motif is one of the most common secondary structin-e elements observed in RNA (17). 

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