Double exponential dendrimer synthesis

Moore et al.[104 106a reported a double exponential dendrimer growth , which is an accelerated convergent process for the synthesis of monodendrons by means of a bidirectional procedure, where the degree of polymerization follows Equation (5.1). 

Figure 12-3 Plots of the degree of polymerization versus the cumulative number of synthetic steps for various repetitive syntheses (a) conventional linear solid-phase synthesis (b) nonlinear straight-chain sequence synthesis (c) dendrimer synthesis (branching multiplicity of three) (d) double exponential den-drimer synthesis (branching multiplicity of three). In all cases, the degree of polymerization is defined as the total number of monomer units per polymer molecule.

Figure 33.6 Double-exponential strategy for dendrimer synthesis.

Recently, new methods such as orthogonal synthesis, double-stage convergent method, double-exponential method, hypermonomer method, and click chemistry have been disclosed for synthesis of dendrimers [5]. 

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