Dot matrix analysis

It can be difficult to decide where exactly to cut a protein so as to cleanly excise each domain. It is not always certain that the duplications that gave rise to the domains happened by the simple duplication of entire domains. Fractions of domains or units containing the C-terminal half of one domain and the N-terminal half of an adjoining domain could, in principle, be duplicated. These pathological cases can be teased out only by close inspection and the careful use of profile analysis and dot-matrix plots (e.g., Gibson et al, 1993). 

Sonnhammer, E. L., Durbin, R. (1995) A dot-matrix program with dynamic threshold control suited for genomic DNA and protein sequence analysis, Gene 167 GC1-10. 

Protein and DNA sequence analysis comprehensive particularly good dot matrix plots... 

Fig. 12. A unidirectional lamina under transverse tension. The points of stress concentration are at the dots. The micromechanical analysis shows that the stress concentration factor increases with volume fraction of fiber and fiber to matrix modulus ratio. From Adams et al.70)...

Large Sized Structures. With an increased amount of deposited material of 3 mg/cm2 and a blending ratio of PS PnBA = 3 7 (weight fraction of the blend component PS 0ps = 0.3) a larger in-plane structure results. A typical optical micrograph is shown in Fig. 8b. Small PS drops are embedded in a PnBA matrix [46], The statistical analysis of the optical micrographs yields a most prominent in-plane length A = 1.13 pm (shown by the red dot in Fig. 5a). 

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