Dose to the patient from a multiple intermittent infusion

4 Dose to the patient from a multiple intermittent infusion 

Notice in this table that Xo/fmf = Q, the infusion rate, which was the same for both regimens in the 

Dosing regimen Infusion rate (Q) [mgh- l Infusion time (U[h]) Dosing interval (t [h]j Dose (mg) Dose/r (proportional to average steady-state drug concentration) (mgh ) 

5 Multiple intermittent infusion of a two-comportment drug vancomycin peak at 1 h post-infusion 

Modification of equations for the time from the end of the infusion to the peak (t )  

---