Sleep attacks dopamine

Common side effects of dopamine agonists are nausea, confusion, hallucinations, lightheadedness, lower-extremity edema, postural hypotension, sedation, and vivid dreams. Less common are compulsive behaviors, psychosis, and sleep attacks. Hallucinations and delusions can be managed using a stepwise approach (Table 55-4). When added to L-dopa, dopamine agonists may worsen dyskinesias. 

Chaudhuri KR, Pal S, Brefel-Courbon C. Sleep attacks or unintended sleep episodes occur with dopamine agonists is this a class effect Drug Saf 2002 25(7) 473-83. 

In 33 patients with Parkinson s disease (mean age 63 years) who were taking a stable dosage of ropinirole in an immediate-release formulation, sleep disturbances improved or disappeared after they switched to a prolonged-release formulation, with improved subjective quality of sleep, reduced daytime sleepiness, and disappearance of sleep attacks [72 ]. The EIDOS and DoTS descriptions of sleep attacks due to dopamine receptor agonists are shown in Figure 4. 

Figure 4 The FIDOS and DoTS descriptions of sleep attacks due to dopamine receptor agonists.

Nervous system Sleep attacks Sleep attacks attributable to dopamine receptor agonists continue to be reported. 

Rose AR, Antic NA, McEvoy RD. Restless leg s3mdrome, dopamine agonists and sleep attacks. Intern Med J 2008 38(11) 872-3. 

Dapsone hemolytic anemia and/or methemoglobinemia Diuretics, loop and thiazide hyponatremia and hypokalemia Dopamine receptor agonists pathological gambling Dopamine receptor agonists sleep attacks Ephedrine ischemic heart disease... 

Dopamine receptor agonists sleep attacks (Chapter 13)... 

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