Domains exon encoding

Bourbon H, Bugler B, Caizergues-Ferrer M, Amalric F (1983) Role of phosphorylation on the maturation pathways of a 100 kDa nucleolar protein. FEBS Lett 155 218-222 Bourbon HM, Lapeyre B, Amalric F (1988) Structure of the mouse nucleolin gene. The complete sequence reveals that each RNA binding domain is encoded by two independent exons. J Mol Biol 200 627-638... 

Keeton, T.P., Burk, S.E., Shull, G.E. (1993). Alternative splicing of exons encoding the calmodulin-binding domains and C termini of plasma membrane Ca2+-ATPase isoforms 1,2,3, and 4. J. Biol. Chem. 268,2740-2748. 

Nrg1tmlGne Targeted mutation 1, Genentech Replacement of the exon encoding the N-terminal half of the EGF domain with a neomycin cassette. This null mutation results in disruption of all splice forms of Nrgl... 

Nrg1tmlLwr targeted mutation 1, Lorna W Role Disruption of the exon 7 by insertion of a nonsense mutation and an Xba1 site in the exon encoding the CRD domain. A lox-P flanked neo gene is also inserted into the intron following the CRD-encoding exon... 

Many exons encode protein domains Section 5,6.2... 

RNA Processing Generates Niature RNA Many Exons Encode Protein Domains... 

Two genes (Pcytla and Pcytlb) encode distinct isoforms of CT, a, and p, respectively. The CTa gene spans approximately 26 kb. Exon 1 is untranslated, exon 2 encodes the translation start site and a nuclear localization signal, exons 4-7 encode the catalytic domain, exon 8 encodes the alpha helical membrane-binding domain, and exon 9 encodes... 

How might the fact that some exons encode discrete functional domains in proteins be related to the evolution of new proteins ... 

The human aggrecan gene resides at chromosome 15q26 (20) and consists of 19 exons (21), with each exon encoding a distinct structural domain of the core... 

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